Have you ever wondered where the magic “10 gram” number comes from when determining a loading dose of amiodarone? In this blog we will review the data surrounding amiodarone loading in patients with atrial fibrillation and hemodynamically stable ventricular arrhythmias.
For patients with atrial fibrillation and structural heart disease, antiarrhythmic options remain limited. Although amiodarone has been a cornerstone of drug therapy in this population, dofetilide is a viable option for many patients. In this piece, we review the safety and efficacy of this often-overlooked drug.